COS, Charlottesville, USA
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Abstract: Barriers to conducting replications – challenges or opportunities?
Interpretation of scientific findings requires the reader to understand what was being tested, how it was tes- ted, how it was analyzed, and what results were obtained. Scientific articles are the primary means to communicate these pieces of information. However, what constitutes as enough information is not always clear or known and varies by discipline, journal, and scientist. Additionally, this varies over time as established methodologies mature and new methodologies emer- ge. This presentation will focus on the barriers encountered when gathering this information as part of the Reproducibility Project: Cancer Biology (https://osf.io/ e81xl/wiki/home/), a project to assess reproducibility rates, predictors of reproducibility, and common obst- acles to conducting replications in preclinical cancer biology. The replications illustrate some of the challenges and opportunities in how research is conducted and communicated.